Pall Mall Barbers are located on an historic site at 27 Whitcomb Street WC2, a narrow street that extends from Pall Mall to Leicester Square at Coventry Street. The street developed out of an ancient highway known as Colman Hedge Lane, which ran from Tyburn Road (now Oxford Street) in the north to the Old Royal Mews, or stables, which stood near the bottom of the lane until they were burned down in 1534. It is now the site of the National Gallery.

Colman Hedge Close, a field of six acres on the west side of Colman Hedge Lane, was owned by Edward Wardour, who gave his name to the northern end of the lane, while the southern end was named after William Whitcomb, a brewer who began building on the west side of the street in the 1670s. The block numbered 27-31, which includes Pall Mall Barbers, dates from this time.

In the same period, Leicester Square was laid out in the fields fronting Leicester House, home of the Earl of Leicester. At the corner of Whitcomb and Orange Streets, the Hand and Racquet public house commemorates the tennis court built in 1634 by Simon Osbaldeston, gentleman barber to the Lord Chamberlain. (Osbaldeston ran another nearby establishment called Shaver’s Hall – not a barber’s shop but a gaming house.)